Article
Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 18 Jan 2006
Burns Marie E, Mendez Ana, Chen Ching-Kang, Almuete Aileen, Quillinan Nidia, Simon Melvin I, Baylor Denis A, Chen Jeannie
Abstract excerpt
Arrestins constitute a family of small cytoplasmic proteins that mediate deactivation of G-protein-coupled receptors (GPCRs) and are known to be essential for cascade inactivation and receptor desensitization. Alternative splicing produces an array of arrestin gene products that have widely different specificities for their cognate receptors in vitro, but the differential functions of these splice variants in...
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