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Article

Visual Arrestin 1 contributes to cone photoreceptor survival and light adaptation.

Investigative ophthalmology & visual science - 1 May 2010

Brown Bruce M, Ramirez Teresa, Rife Lawrence, Craft Cheryl M

Abstract excerpt

PURPOSE: To evaluate morphologic and functional contributions of Arrestin 1 (Arr1) and Arrestin 4 (Arr4) in cone photoreceptors, the authors examined the phenotypes of visual arrestin knockout mice (Arr1(-/-), Arr4(-/-), Arr1(-/-)Arr4(-/-) [Arr-DKO]) reared in darkness. METHODS: Retinal rods and cones were evaluated in wild-type (WT), Arr1(-/-), Arr4(-/-), and Arr-DKO mice using quantitative morphologic analysis,...

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Source

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Identifiers

PMID: 20019357
DOI: 10.1167/iovs.09-4895
PMCID: PMC2864311

Genes

ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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