Article
A role for the light-dependent phosphorylation of visual arrestin.
Proceedings of the National Academy of Sciences of the United States of America - 25 May 1999
Alloway P G, Dolph P J
Abstract excerpt
Arrestins are regulatory proteins that participate in the termination of G protein-mediated signal transduction. The major arrestin in the Drosophila visual system, Arrestin 2 (Arr2), is phosphorylated in a light-dependent manner by a Ca2+/calmodulin-dependent protein kinase and has been shown to be essential for the termination of the visual signaling cascade in vivo. Here, we report the isolation of nine...
Topics
- Alleles
- Animals
- Arrestins
- Drosophila
- Drosophila Proteins
- Electroretinography
- Kinetics
- Light
- Mutagenesis, Site-Directed
- Mutation, Missense
- Phosphoproteins
- Phosphorylation