Article
Visual Cone Arrestin 4 Contributes to Visual Function and Cone Health.
Investigative ophthalmology & visual science - 1 Aug 2015
Deming Janise D, Pak Joseph S, Brown Bruce M, Kim Moon K, Aung Moe H, Eom Yun Sung, Shin Jung-A, Lee Eun-Jin, Pardue Machelle T, Craft Cheryl Mae
Abstract excerpt
PURPOSE: Visual arrestins (ARR) play a critical role in shutoff of rod and cone phototransduction. When electrophysiological responses are measured for a single mouse cone photoreceptor, ARR1 expression can substitute for ARR4 in cone pigment desensitization; however, each arrestin may also contribute its own, unique role to modulate other cellular functions. METHODS: A combination of ERG, optokinetic tracking,...
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