Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo.

doi:10.1126/science.8316831

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Article

Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo.

Science (New York, N.Y.) - 25 Jun 1993

Dolph P J, Ranganathan R, Colley N J, Hardy R W, Socolich M, Zuker C S

Abstract excerpt

Arrestins have been implicated in the regulation of many G protein-coupled receptor signaling cascades. Mutations in two Drosophila photoreceptor-specific arrestin genes, arrestin 1 and arrestin 2, were generated. Analysis of the light response in these mutants shows that the Arr1 and Arr2 protei...

Topics

Amino Acid Sequence
Animals
Animals, Genetically Modified
Arrestins
Drosophila
Drosophila Proteins
Eye Proteins
Female
GTP-Binding Proteins
Genes, Insect
Kinetics
Male
Molecular Sequence Data
Mutation
Phosphoproteins
Photic Stimulation
Photoreceptor Cells
Rhodopsin

Source

Open in PubMed

Identifiers

PMID: 8316831
DOI: 10.1126/science.8316831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8316831-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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