Article
Simian virus 40 small-t antigen stimulates viral DNA replication in permissive monkey cells.
Journal of virology - 1 May 1994
Cicala C, Avantaggiati M L, Graessmann A, Rundell K, Levine A S, Carbone M
Abstract excerpt
The simian virus 40 (SV40) large-T antigen is essential for SV40 DNA replication and for late viral gene expression, but the role of the SV40 small-t antigen in these processes is still unclear. We have previously demonstrated that small t inhibits SV40 DNA replication in vitro. In this study, we...
Topics
- Animals
- Antigens, Viral, Tumor
- Cell Cycle
- Cells, Cultured
- Chlorocebus aethiops
- DNA Replication
- DNA, Viral
- Mice
- Microinjections
- Mutation
- Phosphorylation
- Protein Kinases
- Simian virus 40
- Virus Replication