Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Relationship between MDR1 gene polymorphism and blood concentration of tacrolimus in renal transplant patients].

Zhonghua yi xue za zhi - 7 Dec 2005

Wang Wei, Zhang Xiao-dong, Ma Lin-lin, Lü Yue-ping, Hu Xiao-peng, Zhang Peng, Wang Yong, Guan De-lin

Abstract excerpt

OBJECTIVE: To investigate the relationship between MDR1 exon 21 and exon 26 polymorphism and whole blood concentration of tacrolimus (FK506) in renal transplant patients. METHODS: Blood samples were collected from 86 renal transplant patients who received FK506 peri-operationally. PCR-RELP was used to determine the MDR1 genotype. The patients were divided into 3 subgroups for every position: GG, GT, and TT in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to Gene Frequency

Share to Immunosuppressive Agents

Share to Kidney Transplantation

Share to Tacrolimus

Source

Identifiers

PMID: 16409819

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Relationship between MDR1 gene polymorphism and blood concentration of tacrolimus in renal transplant patients].PMID 16409819Read ↗

Association Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms.Semantic proximity Read ↗

Meta-analysis of the effect of MDR1 C3435 polymorphism on tacrolimus pharmacokinetics in renal transplant recipients.Semantic proximity Read ↗

[Association of CYP3A5 and MDR1 genetic polymorphisms with the blood concentration of tacrolimus in Chinese liver and renal transplant recipients].Semantic proximity Read ↗

Multidrug resistant 1 (MDR1) C3435T and G2677T gene polymorphism: impact on the risk of acute rejection in pediatric kidney transplant recipients.Semantic proximity Read ↗

MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients.Semantic proximity Read ↗

[Effect of MDR1 polymorphic expression on oral disposition of cyclosporine A].Semantic proximity Read ↗

Impact of multidrug resistance 1 gene polymorphism on tacrolimus dose and concentration-to-dose ratio in Chinese liver transplantation recipients.Semantic proximity Read ↗

Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients.Semantic proximity Read ↗

Diltiazem augments the influence of MDR1 genotype status on cyclosporine concentration in Chinese patients with renal transplantation.Semantic proximity Read ↗

The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients.Semantic proximity Read ↗

Amlodipine, but not MDR1 polymorphisms, alters the pharmacokinetics of cyclosporine A in Japanese kidney transplant recipients.Semantic proximity Read ↗

ABCB1 genotypes predict cyclosporine-related adverse events and kidney allograft outcome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.