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Article

Amlodipine, but not MDR1 polymorphisms, alters the pharmacokinetics of cyclosporine A in Japanese kidney transplant recipients.

Transplantation - 15 Sept 2003

Kuzuya Takafumi, Kobayashi Takaaki, Moriyama Natsuko, Nagasaka Takaharu, Yokoyama Itsuo, Uchida Kazuharu, Nakao Akimasa, Nabeshima Toshitaka

Abstract excerpt

BACKGROUND: Cyclosporine A (CsA) is a critical immunosuppressive drug with a narrow therapeutic range and wide interindividual variation in its pharmacokinetics. Many factors, including P-glycoprotein (PGP), influence the oral bioavailability and interpatient variability of CsA. A number of polym...

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Identifiers

PMID: 14501869
DOI: 10.1097/01.TP.0000084873.20157.67

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PGP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14501869-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Amlodipine, but not MDR1 polymorphisms, alters the pharmacokinetics of cyclosporine A in Japanese kidney transplant recipients.PMID 14501869Read ↗

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