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Article

Diltiazem augments the influence of MDR1 genotype status on cyclosporine concentration in Chinese patients with renal transplantation.

Acta pharmacologica Sinica - 1 Jul 2015

Wang Yi-xi, Li Jia-li, Wang Xue-ding, Zhang Yu, Wang Chang-xi, Huang Min

Abstract excerpt

AIM: Co-administration of diltiazem can reduce the dosage of cyclosporine (CsA) in patients with renal transplantation. In this study, we investigated how diltiazem altered the relationship between MDR1 genetic polymorphisms and CsA concentration in Chinese patients with renal transplantation. METHODS: A total of 126 renal transplant patients were enrolled. All the patients received CsA (2-4 mg·kg(-1)·d(-1)), and...

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Identifiers

PMID: 25891084
DOI: 10.1038/aps.2015.6
PMCID: PMC4648117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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