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Article

Meta-analysis of the effect of MDR1 C3435 polymorphism on tacrolimus pharmacokinetics in renal transplant recipients.

Transplant immunology - 1 Aug 2012

Li Yi, Hu Xin, Cai Bei, Chen Jie, Bai Yangjuan, Tang Jiangtao, Liao Yun, Wang Lanlan

Abstract excerpt

BACKGROUND: The published data revealed conflicting results of the polymorphism of MDR1 exon 26 SNP C3435T on the pharmacokinetics of tacrolimus in different post transplant times; thus, the aim was to perform a meta-analysis of different post transplant times to investigate the influence of SNP C3435T on the tacrolimus pharmacokinetics. METHODS: A literature search was conducted to locate the relevant papers by...

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PMID: 22504573
DOI: 10.1016/j.trim.2012.03.006

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