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Article

Age at onset: an essential variable for the definition of genetic risk factors for sporadic Alzheimer's disease.

Annals of the New York Academy of Sciences - 1 Dec 2005

Beyer Katrin, Lao José I, Latorre Pilar, Ariza Aurelio

Abstract excerpt

The aim of our work was to detect minor loci acting as Alzheimer's disease (AD) genetic markers. We divided 206 AD patients and 186 individuals as controls into six age at onset/age-dependent groups. We studied polymorphisms of the genes of apolipoprotein E (APOE) and its promoter, cathepsin D, butyrylcholinesterase, cystatin C, methionine synthase, and cystathionine beta-synthase. Our results demonstrated that...

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Source

Identifiers

PMID: 16399900
DOI: 10.1196/annals.1322.021

Genes

CBS
APOE
CST3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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