Article
The Th1/E47cs-G apolipoprotein E (APOE) promoter allele is a risk factor for Alzheimer disease of very later onset.
Neuroscience letters - 5 Jul 2002
Beyer Katrin, Lao José I, Gómez Milagros, Riutort Nadal, Latorre Pilar, Mate José L, Ariza Aurelio
Abstract excerpt
Several polymorphisms in the apolipoprotein E (APOE) promoter region have been recently described. Of interest, APOE gene expression is increased in association with the -491AT polymorphism T-allele and decreased in relation to the Th1/E47cs polymorphism G-allele. In the present study we have investigated both polymorphisms in a series of 183 Alzheimer disease (AD) patients and 169 controls divided into age at...
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