Article
Alzheimer's disease: genetic polymorphisms and rate of decline.
Dementia and geriatric cognitive disorders - 1 Jan 2012
Schmidt Christian, Wolff Martin, von Ahsen Nicolas, Zerr Inga
Abstract excerpt
BACKGROUND/AIM: To investigate the influence of established genetic risk factors for Alzheimer's disease on the speed of disease progression. METHODS: Polymorphisms (in ACE, ApoE, BIN1, CLU, CR1, CST3, EXOC3L2, GWA14q32.13, IL8, LDLR, PICALM, TNK1) of 40 Alzheimer's disease patients from a longitudinal study were analyzed. A standardized loss of Mini-Mental State Examination points was used as the progression...
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