Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Symptom onset in autosomal dominant Alzheimer disease

16 Jun 2014

Abstract excerpt

OBJECTIVE: To identify factors influencing age at symptom onset and disease course in autosomal dominant Alzheimer disease (ADAD), and develop evidence-based criteria for predicting symptom onset in ADAD. METHODS: We have collected individual-level data on ages at symptom onset and death from 387 ADAD pedigrees, compiled from 137 peer-reviewed publications, the Dominantly Inherited Alzheimer Network (DIAN)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Dementia and Cognitive Impairment Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24928124
DOI: 10.1212/wnl.0000000000000596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Symptom onset in autosomal dominant Alzheimer diseasePMID 24928124Read ↗

The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset.Semantic proximity Read ↗

Late-onset vs nonmendelian early-onset Alzheimer diseaseSemantic proximity Read ↗

Disease duration in autosomal dominant familial Alzheimer diseaseSemantic proximity Read ↗

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.Semantic proximity Read ↗

Clinical and biomarker changes in dominantly inherited Alzheimer's disease.Semantic proximity Read ↗

Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across <i>PSEN1</i> , <i>PSEN2</i> and <i>APP</i> causal genesSemantic proximity Read ↗

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onsetSemantic proximity Read ↗

Age at onset in two common neurodegenerative diseases is genetically controlled.Semantic proximity Read ↗

Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation.Semantic proximity Read ↗

Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer's disease: a case series.Semantic proximity Read ↗

Data-driven models of dominantly-inherited Alzheimer’s disease progressionSemantic proximity Read ↗

Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.