Article
Association and gene-gene interactions of eight common single-nucleotide polymorphisms with pediatric asthma in middle china.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Apr 2010
Wu Xiaohui, Li Yirong, Chen Qingguo, Chen Fenghua, Cai Pengcheng, Wang Lin, Hu Lihua
Abstract excerpt
BACKGROUND: Asthma is a common polygenic disease, caused by complex interactions between multiple genes and environmental factors. Study of the gene-gene interactions would contribute to a new insight into the pathogenesis and therapeutics of asthma. OBJECTIVE: To evaluate the single and combined associations of eight single-nucleotide polymorphisms loci in five candidate genes with the development of asthma in...
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