Article
A common haplotype of interleukin-4 gene IL4 is associated with severe respiratory syncytial virus disease in Korean children.
The Journal of infectious diseases - 1 Nov 2002
Choi Eun Hwa, Lee Hoan Jong, Yoo Taiwoo, Chanock Stephen J
Abstract excerpt
Respiratory syncytial virus (RSV) is a major health problem in young children, and host response to severe disease favors a Th2 immune response. To investigate the genetic basis for RSV disease severity, linked variants of 3 Th2 cytokine genes, IL4, IL13, and IL5 (which are clustered on chromosome 5q31.1) were characterized in 105 children who were hospitalized with severe RSV infection and 315 Korean control...
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