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Article

Polymorphisms in the interleukin 4, interleukin 4 receptor and interleukin 13 genes and allergic phenotype: A case control study.

Advances in medical sciences - 1 Mar 2016

Narożna Beata, Hoffmann Aleksandra, Sobkowiak Paulina, Schoneich Natalia, Bręborowicz Anna, Szczepankiewicz Aleksandra

Abstract excerpt

PURPOSE: Interleukin 4 (IL4), interleukin 4 receptor (IL4R) and interleukin 13 (IL13) play a key role in the pathogenesis of allergy and asthma development. IL4 and IL13 strongly influence bronchial hyperreactivity in response to allergen, airway remodeling, airway inflammation and airway smooth muscle proliferation. Both IL4 and IL13 exert biologic effect via interleukin 4 receptor. The aim of this study was to...

Topics

Adolescent
Case-Control Studies
Child
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Hypersensitivity
Immunoglobulin E
Interleukin-13
Interleukin-4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-4 Receptor alpha Subunit

Male

Phenotype

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 26426602
DOI: 10.1016/j.advms.2015.07.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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