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Article

p45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induced erythroleukemias.

Molecular and cellular biology - 1 Jan 2001

Li Y J, Higgins R R, Pak B J, Shivdasani R A, Ney P A, Archer M, Ben-David Y

Abstract excerpt

In previous studies, we identified a common site of retroviral integration designated Fli-2 in Friend murine leukemia virus (F-MuLV)-induced erythroleukemia cell lines. Insertion of F-MuLV at the Fli-2 locus, which was associated with the loss of the second allele, resulted in the inactivation of the erythroid cell- and megakaryocyte-specific gene p45(NFE2). Frequent disruption of p45(NFE2) due to proviral...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Erythroid-Specific DNA-Binding Factors

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Share to Leukemia, Erythroblastic, Acute

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Source

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Identifiers

PMID: 11113182
DOI: 10.1128/MCB.21.1.73-80.2001
PMCID: PMC88781

Genes

NFE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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p45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induced erythroleukemias.PMID 11113182Read ↗

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