Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathogenesis of Friend leukemia virus.

Leukemia - 1 Apr 1997

Ikawa Y

Abstract excerpt

Friend leukemia virus complex (FLV) consists of replication-defective, Friend spleen focus-forming virus (F-SFFV) and replication-competent, Friend murine leukemia virus (F-MuLV). We produced transgenic mice possessing F-SFFV gp55 gene and clarified that the gp55 glycoprotein encoded by F-SFFV env-related gene is, by itself, responsible for the initiation of erythroleukemia. The occurrence of erythroleukemia,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cytokines
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Mutation

Share to Protein-Tyrosine Kinases

Source

Identifiers

PMID: 9209327

Genes

JAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathogenesis of Friend leukemia virus.PMID 9209327Read ↗

A mouse erythroleukemia cell line possessing friend spleen focus-forming virus gp55 transgene and temperature-sensitive mutant p53 gene.Semantic proximity Read ↗

The envelope glycoprotein of friend spleen focus-forming virus covalently interacts with and constitutively activates a truncated form of the receptor tyrosine kinase Stk.Semantic proximity Read ↗

Friend virus induced murine erythroleukaemia: the p53 locus.Semantic proximity Read ↗

Role of N-terminal sequences of the tyrosine kinase sf-Stk in transformation of rodent fibroblasts by variants of Friend spleen focus-forming virus.Semantic proximity Read ↗

Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line.Semantic proximity Read ↗

Mutation of the Lyn tyrosine kinase delays the progression of Friend virus induced erythroleukemia without affecting susceptibility.Semantic proximity Read ↗

Pathogenicity of a mutant friend spleen focus-forming virus encoding an Env-like membrane glycoprotein (gp55) with substitution by a xenotropic murine leukemia virus Env gp70 sequence.Semantic proximity Read ↗

Loss of p53 tumor suppressor function is required for in vivo progression of Friend erythroleukemia.Semantic proximity Read ↗

Molecular Landscapes and Models of Acute ErythroleukemiaSemantic proximity Read ↗

p45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induced erythroleukemias.Semantic proximity Read ↗

A Friend virus mutant encodes a small glycoprotein that causes erythroleukemia.Semantic proximity Read ↗

Insertional inactivation of the p53 gene during friend leukemia: a new strategy for identifying tumor suppressor genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.