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Article

MYC rearrangements in histologically progressed follicular lymphomas

1 Aug 1992

Abstract excerpt

Histologic transformation of low-grade follicular lymphoma to an aggressive-grade lymphoma occurs in 60% to 80% of patients during their clinical course. The events that drive the transformation process are poorly understood. Deregulation of the MYC gene has been implicated in a small number of cases. This observation led us to examine the molecular organization of the MYC oncogene in 38 cases of histologically...

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Identifiers

PMID: 1638027
DOI: 10.1182/blood.v80.3.758.758

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