Article
Relative frequency and clinicopathologic characteristics of MYC-rearranged follicular lymphoma.
Human pathology - 1 Aug 2021
Chaudhary Shweta, Brown Noah, Song Joo Y, Yang Lin, Skrabek Pamela, Nasr Michel R, Wong Jerry T, Bedell Victoria, Murata-Collins Joyce, Kochan Lindsay, Li Jie, Zhang Weiwei, Chan Wing C, Weisenburger Dennis D, Perry Anamarija M
Abstract excerpt
MYC rearrangement is a relatively rare genetic abnormality in follicular lymphoma (FL). In this study, we evaluated the relative frequency of MYC rearrangement in 522 cases of FL and studied their clinicopathologic, cytogenetic, and molecular characteristics. Fluorescence in situ hybridization studies for MYC (break-apart probe), MYC/IGH, IGH/BCL2, and BCL6 rearrangements were performed on tissue microarrays....
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