Article
Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genes.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jun 2002
Lossos Izidore S, Alizadeh Ash A, Diehn Maximilian, Warnke Roger, Thorstenson Yvonne, Oefner Peter J, Brown Patrick O, Botstein David, Levy Ronald
Abstract excerpt
The natural history of follicular lymphoma (FL) is frequently characterized by transformation to a more aggressive diffuse large B cell lymphoma (DLBCL). We compared the gene-expression profiles between transformed DLBCL and their antecedent FL. No genes were observed to increase or decrease their expression in all of the cases of histological transformation. However, two different gene-expression profiles...
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