Article
p53 mutations are associated with histologic transformation of follicular lymphoma.
Blood - 15 Oct 1993
Lo Coco F, Gaidano G, Louie D C, Offit K, Chaganti R S, Dalla-Favera R
Abstract excerpt
The majority of low-grade non-Hodgkin's lymphomas (NHL) undergo clinical progression toward intermediate- and high-grade lymphomas. This progression is often associated with histologic transformation from follicular to diffuse-type NHL. The pathogenetic mechanisms underlying this evolution are pr...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- Cell Transformation, Neoplastic
- Female
- Gene Deletion
- Genes, myc
- Genes, p53
- Humans
- Lymphoma, Follicular
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation