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Article

Prognostic significance of secondary cytogenetic alterations in follicular lymphomas

21 Aug 2008

Abstract excerpt

Follicular lymphoma (FL) is an indolent lymphoma with a long median survival. Transformation to a more aggressive histology (TLy) is a major cause of mortality. The critical events leading to TLy are unknown. We assessed the prognostic significance of secondary cytogenetic alterations on overall survival (OS) and transformation from 210 diagnostic FL biopsies. We analyzed serial and transformed karyotypes for...

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PMID: 18720523
DOI: 10.1002/gcc.20606

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