Article
Genetic variation in a member of the laminin gene family affects variation in body composition in Drosophila and humans.
BMC genetics - 11 Aug 2008
De Luca Maria, Chambers Michelle Moses, Casazza Krista, Lok Kerry H, Hunter Gary R, Gower Barbara A, Fernández José R
Abstract excerpt
BACKGROUND: The objective of the present study was to map candidate loci influencing naturally occurring variation in triacylglycerol (TAG) storage using quantitative complementation procedures in Drosophila melanogaster. Based on our results from Drosophila, we performed a human population-based association study to investigate the effect of natural variation in LAMA5 gene on body composition in humans. RESULTS:...
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