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Article

Inhibition of protein kinase A in murine enteric neurons causes lethal intestinal pseudo-obstruction.

Journal of neurobiology - 15 Feb 2006

Howe Douglas G, Clarke Christine M, Yan Huijun, Willis Brandon S, Schneider David A, McKnight G Stanley, Kapur Raj P

Abstract excerpt

A number of in vitro studies suggest that many important developmental and functional events in the enteric nervous system are regulated by the intracellular signaling enzyme cAMP protein kinase A (PKA). To evaluate the in vivo significance of these observations, a Cre-inducible, dominant-negative, mutant regulatory subunit (RIalphaB) of PKA was activated in enteric neurons by either a Proteolipid protein-Cre...

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Share to Cyclic AMP-Dependent Protein Kinase RIalpha Subunit
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16329126
DOI: 10.1002/neu.20217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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