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Article

Megaoesophagus in Rassf1a-null mice.

International journal of experimental pathology - 1 Apr 2009

van der Weyden Louise, Happerfield Lisa, Arends Mark J, Adams David J

Abstract excerpt

Megaoesophagus, or oesophageal achalasia, is a neuromuscular disorder characterized by an absence of peristalsis and flaccid dilatation of the oesophagus, resulting in the retention of ingesta in the dilated segment. The aetiology and pathogenesis of idiopathic (or primary) megaoesophagus are still poorly understood and very little is known about the genetic causes of megaoesophagus in humans. Attempts to develop...

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Identifiers

PMID: 19335548
DOI: 10.1111/j.1365-2613.2008.00635.x
PMCID: PMC2676702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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