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Article

Human genetic variation of CYP450 superfamily: analysis of functional diversity in worldwide populations.

Pharmacogenomics - 1 Dec 2012

Polimanti Renato, Piacentini Sara, Manfellotto Dario, Fuciarelli Maria

Abstract excerpt

AIM: The present study aimed to investigate the human genetic diversity of the CYP450 superfamily in order to identify functional interethnic differences and analyze the role of CYP450 enzymes in human adaptation. MATERIALS & METHODS: A computational analysis of genetic and functional differences of the 57 CYP450 genes was performed using the Human Genome Diversity Project and HapMap data; comprising...

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Identifiers

PMID: 23215887
DOI: 10.2217/pgs.12.163

Genes

TBXAS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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