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Article

Genetic variation in the human cytochrome P450 supergene family.

Pharmacogenetics and genomics - 1 Dec 2015

Fujikura Kohei, Ingelman-Sundberg Magnus, Lauschke Volker M

Abstract excerpt

OBJECTIVES: Single nucleotide variations (SNVs) in the cytochrome P450 (CYP) gene family are a primary cause of interindividual differences in therapeutic effects and adverse reactions to drugs. However, we still lack important information on the extent of CYP polymorphisms at the population level. Here, we developed a comprehensive data set of SNVs in all 57 human CYP genes by integrating data from two extensive...

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PMID: 26340336
DOI: 10.1097/FPC.0000000000000172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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