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Article

CYP3A4 and CYP3A5 genotyping by Pyrosequencing.

BMC medical genetics - 9 May 2005

Garsa Adam A, McLeod Howard L, Marsh Sharon

Abstract excerpt

BACKGROUND: Human cytochrome P450 3A enzymes, particularly CYP3A4 and CYP3A5, play an important role in drug metabolism. CYP3A expression exhibits substantial interindividual variation, much of which may result from genetic variation. This study describes Pyrosequencing assays for key SNPs in CYP3A4 (CYP3A4*1B, CYP3A4*2, and CYP3A4*3) and CYP3A5 (CYP3A5*3C and CYP3A5*6). METHODS: Genotyping of 95 healthy European...

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Identifiers

PMID: 15882469
DOI: 10.1186/1471-2350-6-19
PMCID: PMC1142317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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