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Common allelic variants of cytochrome P4503A4 and their prevalence in different populations.

Pharmacogenetics - 1 Mar 2002

Lamba Jatinder K, Lin Yvonne S, Thummel Kenneth, Daly Ann, Watkins Paul B, Strom Stephen, Zhang Jiong, Schuetz Erin G

Abstract excerpt

Marked interindividual variability in expression of CYP3A4 influences the disposition of many endo- and xenobiotics, including the metabolism of steroids, environmental toxins and therapeutically useful drugs. The present study was designed to determine the genetic basis of CYP3A4 variability. We analysed DNA from 82 individuals with known CYP3A4 phenotype including 53 Caucasians and 21 African-American liver...

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PMID: 11875366
DOI: 10.1097/00008571-200203000-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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