Article
Common allelic variants of cytochrome P4503A4 and their prevalence in different populations.
Pharmacogenetics - 1 Mar 2002
Lamba Jatinder K, Lin Yvonne S, Thummel Kenneth, Daly Ann, Watkins Paul B, Strom Stephen, Zhang Jiong, Schuetz Erin G
Abstract excerpt
Marked interindividual variability in expression of CYP3A4 influences the disposition of many endo- and xenobiotics, including the metabolism of steroids, environmental toxins and therapeutically useful drugs. The present study was designed to determine the genetic basis of CYP3A4 variability. We...
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