Article
CCR5, RANTES and CX3CR1 polymorphisms: possible genetic links with acute heart rejection.
Transplantation - 15 Nov 2005
Simeoni Eleonora, Vassalli Giuseppe, Seydoux Charles, Ramsay David, Noll Georg, von Segesser Ludwig K, Fleury Sylvain
Abstract excerpt
BACKGROUND: The inflammation response is modulated by the elaborated chemokine-chemokine receptor system, which also plays an important role in the development of acute rejection (AR). In this study, we hypothesized that functional genetic variants of some of these modulatory proteins might influence the outcome of AR. METHODS: In a retrospective analysis of a cohort of heart transplanted patients (n=158), we...
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