Article
HLA-G +3196 polymorphism as a risk factor for cell mediated rejection following heart transplant.
Human immunology - 1 Apr 2020
Adamson Mitchell B, Di Giovanni Bennett, Ribeiro Roberto V P, Yu Frank, Lazarte Julieta, Rao Vivek, Delgado Diego H
Abstract excerpt
BACKGROUND: Rejection is a leading cause of mortality following heart transplantation. Human leukocyte antigen-G (HLA-G) is an immune checkpoint which dampens the immune response. Reports suggest elevated HLA-G expression is associated with reduced allograft rejection. Our objective was to evaluate HLA-G polymorphisms and cell mediated rejection (CMR) development. METHODS: Recipients (n = 123) were genotyped to...
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