Article
Allograft renal rejection and chemokine polymorphism.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia - 1 Jan 2011
Gorgi Y, Sfar I, Jendoubi-Ayed S, Makhlouf M, Rhomdhane T Ben, Bardi R, Aouadi H, Abdallah T Ben, Abderrahim E, Ayed K
Abstract excerpt
Chemokines play a major role in the process by which leukocytes are recruited from the bloodstream into the sites of inflammation. Genes for the chemokine receptors CCR5, CCR2 and MCP-1 are characterized by functional polymorphisms implicated in transplant rejection. To investigate this association, we analyzed polymorphisms of CCR5-∆32, CCR5-59029-A/G, CCR2-V64I and MCP-1 G/A (-2518) in 173 renal transplant...
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