Article
Genetic variability of major inflammatory mediators has no impact on the outcome of kidney transplantation.
Transplantation - 27 Oct 2007
Brabcova Irena, Petrasek Jan, Hribova Petra, Hyklova Katerina, Bartosova Katerina, Lacha Jiri, Viklický Ondrej
Abstract excerpt
BACKGROUND: Functionally relevant polymorphisms in genes of the Th1 and Th2-inflammatory pathway influence the susceptibility to acute rejection (AR), chronic allograft nephropathy (CAN), and subclinical rejection (SR) as well as graft survival after renal transplantation. Because these findings have not been validated, we sought confirmatory evidence of these associations in a larger group of renal transplant...
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