The recipient CCR5 variation predicts survival outcomes after bone marrow transplantation.

doi:10.1016/j.trim.2017.05.003

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The recipient CCR5 variation predicts survival outcomes after bone marrow transplantation.

Transplant immunology - 1 Jun 2017

Horio Tomohiro, Mizuno Shohei, Uchino Kaori, Mizutani Motonori, Hanamura Ichiro, Espinoza J Luis, Onizuka Makoto, Kashiwase Koichi, Morishima Yasuo, Fukuda Takahiro, Kodera Yoshihisa, Doki Noriko, Miyamura Koichi, Mori Takehiko, Takami Akiyoshi

Abstract excerpt

The chemokine receptor CCR5 plays roles in the trafficking of effector cells towards the site of inflammation. We retrospectively examined the impact of the CCR5 variation (rs1800023, -2086A>G) on transplant outcomes in a cohort of 329 patients who underwent unrelated HLA-matched bone marrow transplantation (BMT) for hematologic malignancies through the Japan Marrow Donor Program. A multivariate analysis showed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allografts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Marrow Transplantation

Share to Disease-Free Survival

Share to Graft vs Host Disease

Share to Hematologic Neoplasms

Share to Infant

Share to Receptors, CCR5

Share to Survival Rate

Source

Open in PubMed

Identifiers

PMID: 28487238
DOI: 10.1016/j.trim.2017.05.003

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The recipient CCR5 variation predicts survival outcomes after bone marrow transplantation.PMID 28487238Read ↗

The recipient CXCL10 + 1642C>G variation predicts survival outcomes after HLA fully matched unrelated bone marrow transplantation.Semantic proximity Read ↗

Donor and recipient chemokine receptor CCR5 genotype is associated with survival after bone marrow transplantationSemantic proximity Read ↗

Single nucleotide polymorphism of CC chemokine ligand 5 promoter gene in recipients may predict the risk of chronic graft-versus-host disease and its severity after allogeneic transplantation.Semantic proximity Read ↗

Toll-like receptor genetic variations in bone marrow transplantation.Semantic proximity Read ↗

Toll-like receptor 1 variation increases the risk of transplant-related mortality in hematologic malignancies.Semantic proximity Read ↗

The effect of CCR5Δ32 on the risk of grade 3-4 acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis.Semantic proximity Read ↗

MHC-resident variation affects risks after unrelated donor hematopoietic cell transplantation.Semantic proximity Read ↗

Polymorphisms in CCR6 are associated with chronic graft-versus-host disease and invasive fungal disease in matched-related hematopoietic stem cell transplantation.Semantic proximity Read ↗

A single-nucleotide polymorphism of the Fcγ receptor type IIIA gene in the recipient predicts transplant outcomes after HLA fully matched unrelated BMT for myeloid malignancies.Semantic proximity Read ↗

The impact of matched and mismatched donor-recipient genotypes for MDR1 polymorphisms (G2677TA, C1236T and C3435T) on the outcomes of patients after allogeneic haematopoietic stem cell transplantation.Semantic proximity Read ↗

Genetic Polymorphisms of Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) and clinical outcomes post-allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis.Semantic proximity Read ↗

Genetic variation in donor CTLA-4 regulatory region is a strong predictor of outcome after allogeneic hematopoietic cell transplantation for hematologic malignancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.