Article
Chemokine receptor polymorphism and risk of acute rejection in human renal transplantation.
Journal of the American Society of Nephrology : JASN - 1 Mar 2002
Abdi Reza, Huong Tran Thi Bich, Sahagun-Ruiz Alfredo, Murphy Philip M, Brenner Barry M, Milford Edgar L, McDermott David H
Abstract excerpt
Chemokines regulate the trafficking of leukocytes in immunity and inflammation and have been implicated in mouse models in acute cardiac and renal allograft rejection; however, their significance to human transplantation is not yet defined. The association of human chemokine receptor genetic variants, CCR5-Delta32, CCR5-59029-A/G, CCR2-V64I, CX3CR1-V249I, and CX3CR1-T280M, with outcome in 163 renal transplant...
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