Article
Lack of association between the -403G/A promoter polymorphism in the human CCL5/RANTES chemokine gene in liver transplant outcome.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Feb 2006
Botella Carmen, Marín Luis, Moya-Quiles Rosa, Miras Manuel, Sánchez-Bueno Francisco, Minguela Alfredo, Bermejo Juan, Parrilla Pascual, Alvarez-López Rocío, Muro Manuel
Abstract excerpt
Chemokines play a major role in the inflammatory and immune responses that mediate allograft outcome. CCL5/RANTES expansion chemokine is potent eosinophil, monocyte, basophils and lymphocyte chemoattractant and has recently been studied in transplantation with discrepant results, but systemic concentrations have been correlated to liver graft survival and incidence of rejection. Recent studies revealed that a...
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