Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock.

Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 2005

Ruoff Peter, Loros Jennifer J, Dunlap Jay C

Abstract excerpt

Temperature compensation is an important property of all biological clocks. In Neurospora crassa, negative-feedback regulation on the frequency (frq) gene's transcription by the FRQ protein plays a central role in the organism's circadian pacemaker. Earlier model calculations predicted that the stability of FRQ should determine the period length of Neurospora's circadian rhythm as well as the rhythm's temperature...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian Rhythm
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Biological

Share to Mutation

Share to Neurospora crassa

Share to Protein Denaturation

Share to RNA, Messenger

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 16314576
DOI: 10.1073/pnas.0505137102
PMCID: PMC1308891

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock.PMID 16314576Read ↗

FRQ-CK1 Interaction Underlies Temperature Compensation of the Neurospora Circadian Clock.Semantic proximity Read ↗

The genetics of circadian rhythms in Neurospora.Semantic proximity Read ↗

Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock.Semantic proximity Read ↗

Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms.Semantic proximity Read ↗

Isoform switching facilitates period control in the Neurospora crassa circadian clock.Semantic proximity Read ↗

Genetic interactions between clock mutations in Neurospora crassa: can they help us to understand complexity?Semantic proximity Read ↗

Setting the pace of the Neurospora circadian clock by multiple independent FRQ phosphorylation events.Semantic proximity Read ↗

The wild-type circadian period of Neurospora is encoded in the residual network of the null frq mutants.Semantic proximity Read ↗

Distinct roles for PP1 and PP2A in the Neurospora circadian clock.Semantic proximity Read ↗

Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination.Semantic proximity Read ↗

Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation.Semantic proximity Read ↗

CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.