Article
FRQ-CK1 Interaction Underlies Temperature Compensation of the Neurospora Circadian Clock.
mBio - 29 Jun 2021
Hu Yue, Liu Xiaolan, Lu Qiaojia, Yang Yulin, He Qun, Liu Yi, Liu Xiao
Abstract excerpt
Temperature compensation is a fundamental property of all circadian clocks; temperature compensation results in a relatively constant period length at different physiological temperatures, but its mechanism is unclear. Formation of a stable complex between clock proteins and casein kinase 1 (CK1) is a conserved feature in eukaryotic circadian mechanisms. Here, we show that the FRQ-CK1 interaction and CK1-mediated...
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