Article
[The influence of -238 and -308 TNF alpha polymorphisms on the pathogenesis and response to treatment in rheumatoid arthritis].
Revista medica de Chile - 1 Sept 2005
Llanos Carolina, Soto Lilian, Sabugo Francisca, Bastías M José, Salazar Lorena, Aguillón Juan C, Cuchacovich Miguel
Abstract excerpt
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects 0.8% of the world population, it affects the synovial membrane of joints and the clinical presentation encompasses a wide spectrum, ranging from a mild to a severe and erosive disease that causes joint and cartilage destruction which finally provokes irreversible structural damage and patient disability. In the last years, there have been...
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