Article
Association of polymorphisms in promoter region of TNF-α -238 and -308 with clinical outcomes in patients with immune-mediated inflammatory diseases on anti-TNF therapy.
Rheumatology international - 1 Dec 2021
Miler Marijana, Nikolac Gabaj Nora, Ćelap Ivana, Grazio Simeon, Tomašić Vedran, Bišćanin Alen, Mitrović Joško, Đerek Lovorka, Morović-Vergles Jadranka, Vrkić Nada, Štefanović Mario
Abstract excerpt
The hypothesis of the study was that polymorphisms in promoter regions -238 and -308 of TNF-α could be associated with different clinical outcomes in inflammatory bowel diseases (IBD) and immune-mediated rheumatic diseases (IMRD). The aim was to examine the possible association of both polymorphisms with concentration of C-reactive protein (CRP) and fecal calprotectin (fCAL), onset of the remission and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.