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Article

TNF-α and TNF-β Gene Polymorphism in Saudi Rheumatoid Arthritis Patients

1 Jan 2011

Abstract excerpt

BACKGROUND: Tumor necrosis factor (TNF)-α and -β are cytokines with a wide range of inflammatory, apoptotic and immunomodulatory activities. TNF-α promoter -308 G < A polymorphism has been reported to be associated with rheumatoid arthritis (RA) with inconsistent results. OBJECTIVE: The aim of this study is to elucidate a possible association of TNF-α (G-308A) and TNF-β (A+252G) polymorphisms with the...

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PMID: 21792343
DOI: 10.4137/cmamd.s6941

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