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Article

[Tumor necrosis factor alpha genetic polymorphism as a risk factor in disease].

Revista medica de Chile - 1 Sept 2002

Aguillón Juan C, Cruzat Andrea, Cuenca Jimena, Cuchacovich Miguel

Abstract excerpt

Cytokine unbalance is responsible for the pathogenesis of diverse inflammatory, autoimmune and infectious diseases, and Tumor Necrosis Factor Alpha (TNF alpha), among other cytokines, plays a central role. TNF alpha production can be regulated at the transcriptional, post-transcriptional, and translational levels. Variability in the promoter and coding regions of the TNF alpha gene may modulate the magnitude of...

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PMID: 12434654

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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