Article
TNF gene promoter region polymorphisms and association with young-onset rheumatoid arthritis.
Pakistan journal of pharmaceutical sciences - 1 Sept 2019
Fatima Rizvi Syeda Taskeen, Arif Afsheen, Azhar Abid
Abstract excerpt
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that shares a major global economic burden due to disabilities and mortality risk. It affects all age groups with a female predominance. Tumor Necrosis Factor (TNF) a proinflammatory cytokine is one of the key players in etiology of autoimmune diseases such as RA. TNF gene promoter polymorphisms predict disease susceptibility, severity and...
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