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Article

Wnt/Axin1/beta-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries.

Neuron - 2 Aug 2007

Carl Matthias, Bianco Isaac H, Bajoghli Baubak, Aghaallaei Narges, Czerny Thomas, Wilson Stephen W

Abstract excerpt

Nodal activity in the left lateral plate mesoderm (LPM) is required to activate left-sided Nodal signaling in the epithalamic region of the zebrafish forebrain. Epithalamic Nodal signaling subsequently determines the laterality of neuroanatomical asymmetries. We show that overactivation of Wnt/Axin1/beta-catenin signaling during late gastrulation leads to bilateral epithalamic expression of Nodal pathway genes...

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Identifiers

PMID: 17678853
DOI: 10.1016/j.neuron.2007.07.007
PMCID: PMC1940036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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