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Article

Establishment of vertebrate left-right asymmetry.

Nature reviews. Genetics - 1 Feb 2002

Hamada Hiroshi, Meno Chikara, Watanabe Daisuke, Saijoh Yukio

Abstract excerpt

The generation of morphological, such as left-right, asymmetry during development is an integral part of the establishment of a body plan. Until recently, the molecular basis of left-right asymmetry was a mystery, but studies indicate that Nodal and the Lefty proteins, transforming growth factor-beta-related molecules, have a central role in generating asymmetric signals. Although the initial mechanism of...

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Identifiers

PMID: 11836504
DOI: 10.1038/nrg732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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