Article
Genetic and immunological parameters governing in vivo susceptibility/resistance to retrovirally induced murine malignant histiocytosis.
Journal of leukocyte biology - 1 Oct 1998
Panoskaltsis-Mortari A, Egeler R M, Yaeger T M, Yoneji S, Schmitz L, Lilly F, Nesbit M E, Blazar B R
Abstract excerpt
Malignant histiocytosis sarcoma virus (MHSV) arose as a recombinant of c-Harvey-ras murine sarcoma virus (Ha-MuSV) and Friend mink cell focus-forming virus (F-MCFV). It is a defective acute transforming retrovirus that, along with Friend murine leukemia helper virus (F-MuLV), induces malignant histiocytosis (MH) in susceptible adult mice. We have assessed the in vivo susceptibility to MHSV in inbred homozygous,...
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