Article
Immunity to retroviral infection: the Friend virus model.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 1997
Hasenkrug K J, Chesebro B
Abstract excerpt
Friend virus infection of adult immunocompetent mice is a well established model for studying genetic resistance to infection by an immunosuppressive retrovirus. This paper reviews both the genetics of immune resistance and the types of immune responses required for recovery from infection. Specific major histocompatibility complex (MHC) class I and II alleles are necessary for recovery, as is a non-MHC gene,...
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