Article
Host genetic factors that control immune responses to retrovirus infections.
Vaccine - 6 Jun 2008
Miyazawa Masaaki, Tsuji-Kawahara Sachiyo, Kanari Yasuyoshi
Abstract excerpt
Several host genes control retroviral replication and pathogenesis. These include genes that directly affect the replication of retroviruses in target cells and those that control the host immune responses to the viral antigens. Host genetic factors that affect retroviral replication and immune responses to the viral antigens have been best studied in mouse models of Friend leukemia virus (FV) infection. Several...
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